AFIL is an Italian private non-profit association, recognized by Lombardy Region as the regional technological cluster for Advanced Manufacturing. AFIL is the outcome of a Lombardy-Region-led process aiming to set up a network of clusters interested in carrying out, at the national and international level, an integrated and sustainable system of infrastructures, competencies and methodologies supporting research and innovation. It represents a network of companies, universities, public or private research institutions and entities operating in the field of intelligent factories (Advanced Manufacturing). AFIL’s members are located in different territorial areas and focused on specific application fields. The cluster aims to promote and facilitate research and innovation to build best practices and enable technologies for the manufacturing sector to support and develop the Lombardy production system’s leadership and competitiveness.